Endocrine Abstracts

Introduction: Indirect calorimetry is the most frequently used method to measure resting energy expenditure (REE), but the great expense of equipment precludes its widespread use. The best known REE calculation formula is the ‘Harris and Benedict Formula’. The aim of this study is to assess the impact of glucose metabolism status on REE.Methods: Data from 110 subjects with impaired glucose tolerance (IGT), 108 subjects with impaired fasting glu...

Introduction: Increased neutrophil to lymphocyte ratio (NLR) is an inflammatory marker and an indicator of cardiovascular risk. Recent studies demonstrated that the NLR values of the diabetic patients were significantly higher than the healthy controls. Vitamin D (25OHD) deficiency has been associated with diabetes mellitus and cardiovascular diseases. Studies established a significant negative correlation between 25(OH)D and HbA1c levels. Aim of this study is to evaluate the ...

Introduction: Riedel’s thyroiditis (RT) is a rare and chronic fibro-inflammatory disease firstly described by Riedel in 1896. It is characterized by a dense fibrosis that replaces normal thyroid parenchyma. The fibrotic process invades adjacent structures of the neck and extends beyond the thyroid capsule, which differentiates RT from other inflammatory or fibrotic disorders of the thyroid. The overall incidence in outpatients is 1.06 per 100 000. We presented here a case...

Objective: Platelet activation and aggregation play major role in the pathophysiology of atherothrombosis. Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherosclerosis. The present study was designed to evaluate levels of MPV before and after the levothyroxine (L-T4) treatment in patients with overt hypothyroidism.Materials and methods: The study included 30 Hashimoto’s...

Aim: Acromegaly is associated with accelerated atherosclerosis and cardiovascular disease. Nitric oxide (NO) is enzimatically formed from L-arginine by endothelial nitric oxide synthase (eNOS). Several studies have shown that reduction in NO synthesis causes endothelial dysfunction and impaired endothelium-dependent vasodilation. Asymmetric dimethylarginine (ADMA), the endogenous inhibitor of NOS, accumulation plays a prominent role in the pathogenesis and in pr...